oral activity — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T5405	BI-1347		CDK
	BI-1347 is a potent, selective inhibitor of CDK8/cyclinC (IC50: 1 nM). It shows tumor growth inhibition in an in vivo xenograft model.		CDK
T7938	Quinidine		Parasite
	Quinidine is a stereoisomer of the antimalarial agent quinine and a class Ia antiarrhythmic agent. for the treatment of abnormal heart rhythms and also malaria.		Parasite
T3465	Vesnarinone	OPC-8212,Arkin,Piteranometozine	HIV Protease , PDE
	Vesnarinone (Arkin) (INN) is a mixed phosphodiesterase 3 inhibitor and ion-channel modifier that has modest, dose-dependent, positive inotropic activity, but minimal negative chronotropic activity. It also suppresses cel...		HIV Protease , PDE
T0687	Simvastatin	MK-0733,MK 733	Apoptosis , Mitophagy , Ferroptosis , HMG-CoA Reductase , Autophagy
	Simvastatin (MK 733) is an HMG-CoA reductase inhibitor (Ki=0.2 nM) with oral activity. Simvastatin has hypolipidemic activity, inhibits hepatic production of cholesterol, and is also used for the prevention of cardiovasc...
T8125	Quinidine sulfate dihydrate	Chinidin Sodium,β-quinine Sodium,Pitayine Sodium,Quinidine sulfate	P450
	Quinidine sulfate dihydrate (Pitayine Sodium) is a potent and selective cytochrome P450db inhibitor		P450
T20198	Potassium gluconate	Kalium-beta,Kalium Gluconate,Kaon elixir,Kaon,Potassium D-gluconate,HSDB 3165,K-Iao	Endogenous Metabolite , Antifungal
	Potassium gluconate (Potassium D-gluconate) is an oxidizing carboxylic acid with oral activity and chelating properties with bactericidal activity.		Endogenous Metabolite , Antifungal
T67991	Iliparcil		Others
	Iliparcil is an antithrombotic compound with oral activity.		Others
T26914	BTA-9881	BTA9881,AZD9639,AZD-9639,BTA 9881,MEDI-564	RSV
	BTA-9881 is a novel RSV fusion inhibitor with oral activity and antiviral activity for the study of respiratory syncytial virus infections.		RSV
T23449	TCS 46b		NMDAR
	NR1A/NR2B NMDA receptor antagonist,orally active		NMDAR
T8263	3,4'-Dihydroxyflavone		Influenza Virus
	3,4'-Dihydroxyflavone (3,4'-DHF) is an oral active flavonoid. 3,4'-Dihydroxyflavone (3,4'-DHF) shows antiviral activity against Influenza A virus.		Influenza Virus
T13312L	Seviteronel	VT-464	Others
	Seviteronel is an effective CYP17 lyase inhibitor (h-Lyase IC50=69 nM). In a hamster model of androgen biosynthesis inhibition, it demonstrated both exceptional in vitro lyase/hydroxylase selectivity (~10-fold) and oral...		Others
T7120	Cefetamet pivoxil hydrochloride	Ro 15-8075	Antibacterial , Antibiotic
	Cefetamet pivoxil hydrochloride (Ro 15-8075) is a third generation cephalosporin antibiotic with oral activity.		Antibacterial , Antibiotic
T12894	SGN-2FF		Others
	SGN-2FF is an oral fucosylation inhibitor and inhibits fucosyltransferase activity, and has antitumor activity.		Others
T34616	Seridopidine	ACR-343,ACR 343,ACR343	Dopamine Receptor
	Seridopidine (ACR343) is a modulator of dopaminergic activity that is used as an oral therapy for schizophrenia, Parkinson's disease, and Tourette's syndrome.		Dopamine Receptor
T2492	Perifosine	NSC 639966,D21266,KRX-0401	Apoptosis , Akt , Autophagy
	Perifosine (KRX-0401) is an oral-active, alkyl-phosphocholine Akt inhibitor with potential antineoplastic activity.		Apoptosis , Akt , Autophagy
T9593	Senaparib	IMP4297	PARP
	Senaparib (IMP4297) is a novel highly potent and selective oral PARP1/2 inhibitor with strong antitumor activity.		PARP
T1687	Doxycycline	Vibramycin,Doxiciclina,Doxytetracycline,Doxycyclinum	MMP , ribosome , Antibacterial , Antibiotic , Parasite
	Doxycycline (Doxiciclina) belongs to the tetracycline class of antibiotics and is a broad-spectrum metalloproteinase (MMP) inhibitor with oral activity. Doxycycline has antibacterial activity and antitumor activity.		MMP , ribosome , Antibacterial , Antibiotic , Parasite
T67875	DHODH-IN-23		Dehydrogenase
	DHODH-IN-23 is a DHODH inhibitor with oral activity. DHODH-IN-23 is often used in cancer research.		Dehydrogenase
T33711L	Nolomirole HCl	CHF 1035 HCl,CHF 1035,CHF1035,CHF1035 HCl,CHF-1035 HCl,CHF-1035,Nolomirole Hydrochloride	Dopamine Receptor , Norepinephrine
	Nolomirole HCl (CHF 1035) is a novel selective dopamine agonist with oral activity and inhibitory effects on norepinephrine release, which can be used to study mild chronic heart failure.		Dopamine Receptor , Norepinephrine
T1687L	Doxycycline (hyclate)	Doxycycline hydrochloride hemiethanolate hemihydrate,WC2031,Doxycycline hyclate	MMP , ribosome , Antibacterial , Antibiotic
	Doxycycline hyclate (WC2031) belongs to the tetracycline class of antibiotics and is a broad-spectrum metalloproteinase (MMP) inhibitor with oral activity. Doxycycline hyclate has antibacterial activity and antitumor act...		MMP , ribosome , Antibacterial , Antibiotic